ioncube, centos x64

go http://www.ioncube.com/loaders.php
download for your platform and php version
tar zxf ioncube_loaders_all_platforms.tar.gz
cd ioncube/
mv ioncube_loader_lin_5.3.so /usr/lib64/php/modules
vim /etc/php.d/ioncube-loader.ini
and enter there
zend_extension=/usr/lib64/php/modules/ioncube_loader_lin_5.3.so